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. 2015 May 20;2015(5):CD007929. doi: 10.1002/14651858.CD007929.pub3
Study Reason for exclusion
Ashworth 2008 Review article
Audeh 2009 Phase II, single‐arm trial of the oral PARP inhibitor OLA (AZD2281) in BRCA‐deficient advanced ovarian cancer (ASCO 2009 meeting abstract)
Audeh 2010 Non‐randomised, phase II, single‐arm study (update of Audeh 2009)
Banerjee 2013 Review article
Chen 2013 Review article
Coleman 2014 Non‐randomised phase II trial; no control group
Drew 2008 Review article
Fong 2006 Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of a small molecule inhibitor of Poly(ADP‐ribose) polymerase (PARP), KU‐0059436 (Ku) in patients with advanced tumours (ASCO 2006 meeting abstract)
Fong 2008 Results from a phase I study of AZD2281 (KU‐0059436), a PARP (poly(ADP‐ribose) polymerase) inhibitor with single‐agent anticancer activity in patients with BRCA‐deficient ovarian cancer (ASCO 2008 meeting abstract)
Fong 2009 Non‐randomised phase I clinical trial analysing the pharmacokinetic and pharmacodynamic characteristics of OLA (AZD2281). Selection was aimed at having a study population enriched in carriers of a BRCA1 or BRCA2 mutation
Gelmon 2011 Phase 2, multicentre, open‐label, non‐randomised study
Helleday 2008 Review article
Lee 2014 Biomarker study of RCT comparing olaparib plus/minus cediranib: wrong comparison and wrong outcomes
Lord 2008 Review article
Lui 2014 Comparison of Olaparib versus Olaparib and Cediranib ‐ no randomisation of Olaparib; 2 references to this study.
Moore 2014 On‐going study but study on effects of high fat food on pharmacokinetics
Muggia 2009 Review article
NCT01891344 Ongoing, non‐randomised, open‐label, phase II study (Ariel2)
Shaw 2013 Review article
Turner 2005 Review article
Yap 2007 Phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of KU‐0059436 (Ku), a small molecule inhibitor of poly(ADP‐ribose) polymerase (PARP) in cancer patients, including BRCA1/2 mutation carriers (ASCO 2007 meeting abstract)
Yap 2009 Review article

OLA: olaparib