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. 2016 Sep 18;2016(9):CD006992. doi: 10.1002/14651858.CD006992.pub2

Sheu 2015.

Methods Randomised double‐blind trial
Participants Asian participants with type 2 diabetes mellitus inadequately controlled by basal insulin with/without oral agents
Interventions Treatment with linagliptin 5 mg once daily or placebo. Basal insulin dose remained stable for 24 weeks, after which adjustments could be made according to the investigator's discretion to improve glycaemic control
Outcomes HbA1c, adverse events
Notes Need to determine if subgroup analysis with insulin monotherapy is possible