Date	Event	Description
27 March 2013	New search has been performed	A search of the Cystic Fibrosis & Genetic Disorders Review Group's Cystic Fibrosis Register identified five new references to four studies potentially eligible for inclusion in this review; all were excluded (Adeboyeku 2011; Keel 2011; Riethmueller 2009; Semykin 2010).
27 March 2013	New citation required but conclusions have not changed	No new studies were included in this update of the review, therefore our conclusions have not changed.
3 December 2010	New search has been performed	A search of the Group's Cystic Fibrosis Register identified six new references. The references were all excluded from this review, as was the one outstanding reference awaiting classification from the original review (Hjelte 1988).
3 December 2010	New citation required but conclusions have not changed	The lead author (Martin Wildman) has stepped down from this role, but remains a co‐author on this review. The lead author is now Amanda Plummer. One author (Bryan Fernandes) has left the author team.
1 April 2008	New search has been performed	A search of the Group's Cystic Fibrosis Trials Register did not identify any references eligible for inclusion in this review.
31 March 2008	Amended	Converted to new review format. Post hoc change: see Long‐term outcomes two primary outcome measures have been more appropriately re‐classified as secondary outcome measures.