Borgelt 1981

Methods	RCT (2 studies) study 1: enrolled: 155 evaluated: 138 study 2: enrolled: 78 evaluated: 64
Participants	Inclusion: 1. Brain metastases diagnosed by clinical symptoms and EEG, radioisotope brain scans, arteriograms, pneumoencephalograms, or biopsy Exclusion: ‐medical condition precluding adequate follow up ‐new anti‐cancer treatment within two weeks ‐lesions too numerous ‐symptoms too vague for adequate assessment
Interventions	Study 1: 1000 cGy/1 fr 3000 cGy ‐ 4000 cGy/10‐20 fr Study 2: 1200 cGy/ 2 fr 2000 cGy/5 fr
Outcomes	1. Survival 2. Improvement in neurologic function (3. Treatment morbidity)
Notes	QS = 2