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. 2012 Apr 18;2012(4):CD003869. doi: 10.1002/14651858.CD003869.pub3

Davey 2008

Methods RCT
evaluated: 90
Participants confirmed malignant disease
brain metastases
ECOG performance status 0‐2
excluded patients with complete excision of a single brain metastasis and life expectancy less than 6 weeks
Interventions whole brain radiotherapy 40 Gy in 20 fractions twice daily
versus
whole brain radiotherapy 20 Gy in 5 fractions once daily
Outcomes Primary:
overall survival
Notes