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Graham 2010
| Methods | RCT: evaluated: 113 |
|
| Participants | ECOG performance status <3 life expectancy > 2 months extracranial disease (stable for 2 months, or absent or concurrent with brain metastases at time of initial cancer diagnosis) |
|
| Interventions | whole brain radiotherapy 40 Gy in 20 twice daily fractions versus whole brain radiotherapy 20 Gy in 4 daily fractions |
|
| Outcomes | primary: intracranial control and quality of life secondary: interval to CNS progression overall survival |
|
| Notes | ||
