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. 2012 Apr 18;2012(4):CD003869. doi: 10.1002/14651858.CD003869.pub3

Horton 1971

Methods RCT: evaluated: 47
Participants Inclusion: 1. Histologically proven cancer 2. Parenchymal brain metastases (radio‐isotope brain scans, EEG, echo‐encephalograms, angiograms, spinal fluid cytology and chemistry)
Exclusion: 1. All gross brain tumour surgically excised
Interventions Supportive care (oral prednisone) versus Supportive care (oral prednisone) and WBRT
Outcomes 1. Survival 2. Improvement in performance status
Notes QS =2