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Komarnicky 1991
| Methods | RCT: enrolled: 859 evaluated: 779 | |
| Participants | Inclusion: 1. Brain metastases with measurable disease 2. 18 to 75 years of age 3. KPS ≥ 40 4. Neurologic function class (NFC) 1, 2, 3 5. If on chemo must not have had change in drugs within two weeks prior to randomization, during RT/misonidazole or two weeks after completion of RT | |
| Interventions | 3000 cGy/10 fr and misonidazole versus 3000 cGy/10 fr | |
| Outcomes | 1. Survival | |
| Notes | QS = 3 | |
