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. 2012 Apr 18;2012(4):CD003869. doi: 10.1002/14651858.CD003869.pub3
Trial name or title Protocol ID: 040066 Surgery versus radiosurgery to treat metastatic brain tumors
Methods
Participants Eligibility: 1. histologically confirmed cancer 2. one to three brain metastases 3. less than or equal to 4 cm
Exclusion: 1. brainstem lesions 2. tumours within 10 mm from optic apparatus 3. poor operative candidates 4. leptomeningeal disease 5. psychiatric impairments 6. infection 7. germ cell tumour, lymphoma, small cell lung cancer
Interventions Surgery versus radiosurgery
Outcomes 1. survival 2. tumour recurrence or progression 3. neurologic sign or symptom developmen 4. functional independencet 5. steroid and anticonvulsant use 6. quality of life
Starting date
Contact information
Notes