Andrews 2004
| Methods | RCT enrolled: 333 evaluated: 331 | |
| Participants | Inclusion: 1. 1‐3 brain metastases 2. maximum size 4 cm (largest lesion) and others not more than 3 cm Exclusion: 1. KPS < 70 2. brainstem metastasis 3. metastasis less than 1 cm from optic apparatus 4. active extracranial disease judged by systemic treatment given within 1 month of enrollment | |
| Interventions | WBRT and radiosurgery boost vs WBRT | |
| Outcomes | 1. Overall survival 2. Local control, overall intracranial recurrence rates 3. cause of death 4. performance status 5. steroid usage | |
| Notes | QS = 3 | |