Barriga 1997

Methods	Double blind randomisation
Participants	N = 83 adults and paediatric patients with various malignancies, mainly leukaemia; 143 febrile episodes recorded
Interventions	Vancomycin/heparin versus heparin‐only flush (25 ug/ml vanco and 25 units/ml heparin)
Outcomes	*Bacteraemia (BSI) *Vanco‐sensitive organism bacteraemia
Notes	A difference was stated in neutropenia and non‐neutropenia
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate