Henrickson 2000

Methods	Double blind randomisation Stratified for risk groups
Participants	N = 126 paediatric patients (44% ALL, 40% solid, 7 % BMT). There were 153 assessable TCVCs
Interventions	Vancomycin/heparin versus heparin only flush (25 ug/ml vanco and 100 units/ml heparin)
Outcomes	*Exit‐site infection *Bacteraemia (CRBSI) *Time to first infection
Notes	The third group included vanco/heparin ciprofloxacin Quantitative cultures were done
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate