Ranson 1990

Methods	Double blind randomisation
Participants	N = 98 adults A) N = 48 and 35 catheters, acute leukaemia and BMT B) N = 50 and 37 catheters (solid tumour)
Interventions	Vancomycin versus control (2 doses one prior to insertion, one after positioning of the catheter) 500 mg vanco
Outcomes	*Catheter‐related sepsis in first 30 days *Tunnel sepsis *Coagulase negative staphylococcal bacteraemia
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate