Vassilomaniakis 1995

Methods	Randomisation by cards in closed envelopes
Participants	N = 40 adult patients
Interventions	Vancomycin versus control (vanco in 3 doses of 500 mg 1 hr prior to insertion, 6 and 12 h afterwards)
Outcomes	*Exit‐site infection *CRBSI *Gram positive infections
Notes	Only initially randomised
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Unclear risk	B ‐ Unclear

CRS = catheter‐related sepsis; BMT = bone marrow transplant; TCVC = tunnelled central venous catheter; TPN = total parenteral nutrition; CVC = central venous catheter; TID = totally implantable device; CRBSI = catheter‐related blood stream infection