Ishikawa 2006

Methods	Case‐control study through a pooled analysis of two prospective cohort studies,Japan
Participants	78,950 cohort participants 78 cases, sub‐cohort control
Interventions	N/A
Outcomes	Incidence Adjusted for age, smoking, alcohol, tea and coffee consumption
Cancer type & time of follow‐up	Esophageal cancer
Sponsor	Not declared
Notes	Pooled hazard ratio for both cohorts: Never or occasionally HR = 1.00 1 to 2 cups/day:HR = 1.03 (95% CI 0.46 to 2.28) 3 to 4 cups/day: HR = 1.13 (95% CI 0.53 to 2.42) 5 cups or more/day: HR = 1.67 (95% CI 0.89 to 3.16) p = 0.04