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. 2013 Aug 23;2013(8):CD008588. doi: 10.1002/14651858.CD008588.pub2
Feature Thymoma Thymic carcinoma
Organotypic (thymus‐like)
histological features Almost always present (lobular
pattern, perivascular spaces,
immature, TdT+/CD1a+/CD99+ T to cells) None or abortive
CD5, CD70 and CD117 expression
in epithelial cells No Frequent (~ 60%)
Invasion Variable Almost always
Myasthenia gravis Variable: 10% to 80% No
Other autoimmune diseases Common Rare
Clinical behaviour Often curable by surgery;
metastases are rare
Usually long survival due to
indolent clinical course Often unresectable; metastases are frequent
Often short survival due to progressive
disease