Table 1.
The effect of the SIRT1 inhibitors on the numbers of mES cell-derived hematopoietic colonies
| Colony type | CON | NAM | SP |
|---|---|---|---|
| BFU-E | 9.5±3.36 | 12.8±3.67 | 14.4±3.50 |
| CFU-E | 40.9±4.59 | 65.9±7.80 | 49.3±4.56 |
| CFU-GM | 31.5±4.45 | 43.9±6.57 | 44.4±5.24 |
| CFU-GEMM | 27.3±4.76 | 30.3±5.36 | 24.2±3.60 |
| 2nd EB | 31.6±4.87 | 30.3±3.72 | 27.2±4.16 |
| Total | 140.8±11.96 | 183.2±15.02 | 159.5±6.60 |
The total numbers of BFU, CFU-E, CFU-GM, CFU-GEMM, and 2nd EB in each group were scored by microscopy on day 7. Values are expressed as the mean±standard error of the mean per 104 cells (n=9). BFU-E: burst forming unit-erythroid, CFU-E: colony forming units-erythroid, CFU-GM: colony forming unit-granulocyte, macrophage, CFU-GEMM: colony forming unit-granulocyte, erythrocyte, macrophage, megakaryocyte, 2nd EB: secondary embryoid body.