Comparison 1. Exercise versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Physical fitness	20	1310	Std. Mean Difference (IV, Random, 95% CI)	0.42 [0.25, 0.59]
2 Fatigue	22	1698	Std. Mean Difference (IV, Random, 95% CI)	‐0.28 [‐0.41, ‐0.16]
3 Cancer‐specific quality of life	13	1012	Std. Mean Difference (IV, Random, 95% CI)	0.12 [‐0.00, 0.25]
4 Health‐related quality of life	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
5 Cancer site‐specific quality of life	4	262	Mean Difference (IV, Random, 95% CI)	4.24 [‐1.81, 10.29]
6 Depression	6	674	Std. Mean Difference (IV, Random, 95% CI)	‐0.15 [‐0.30, 0.01]
7 Cognitive function	2	213	Mean Difference (IV, Random, 95% CI)	‐11.55 [‐22.06, ‐1.05]
8 Strength	13	912	Std. Mean Difference (IV, Random, 95% CI)	0.27 [0.04, 0.50]
9 Subjective upper body function	3	231	Mean Difference (IV, Random, 95% CI)	‐0.52 [‐4.45, 3.41]
10 Shoulder mobility	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
11 Arm morbidity	3	240	Mean Difference (IV, Random, 95% CI)	1.11 [‐4.07, 6.29]
12 Anxiety	3	331	Mean Difference (IV, Random, 95% CI)	‐1.45 [‐4.36, 1.46]
13 Mood disturbances	3	111	Std. Mean Difference (IV, Random, 95% CI)	‐1.00 [‐1.40, ‐0.60]
14 Hospital Anxiety and Depression Scale	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
15 Self esteem	4	323	Mean Difference (IV, Random, 95% CI)	1.69 [‐0.01, 3.39]
16 Physical activity	8	549	Std. Mean Difference (IV, Random, 95% CI)	0.29 [0.12, 0.47]
17 Neuropathic pain	2	130	Mean Difference (IV, Random, 95% CI)	3.64 [‐1.32, 8.60]
18 Neuropathy symptoms	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
19 Endocrine symptoms	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
20 Gait and balance	3	122	Std. Mean Difference (IV, Random, 95% CI)	0.10 [‐0.25, 0.46]
21 Lymphoedema incidence	4	436	Risk Ratio (M‐H, Random, 95% CI)	0.71 [0.35, 1.45]