Schwartz 2007 AET.

Methods	RCT, parallel 3‐group design, stratified according to menopausal status (premenopausal or postmenopausal). Study start and stop dates: not reported Length of intervention: 6 months Length of follow‐up: end of intervention
Participants	72 breast cancer patients, stages I to III (histologically confirmed); planning to begin chemotherapy with doxorubicin or methotrexate and receiving a glucocorticoid as part of the antiemetic regimen. Strenuous regular exercisers, that is women who exercised more than 250 minutes per week, were excluded
Interventions	Intervention group 1 (n = 22): 'Schwartz AET' Aerobic exercise training (participant preferences); 77% weight‐bearing activities (walking/running), 15 to 30 minutes, 4 days per week Intervention group 2 (n = 21): 'Schwartz RET' Resistance exercise (Thera‐Band), 2 sets of 8 exercises (4 upper and 4 lower body) Control group (n = 23): usual care, women were instructed to continue usual activities, were not instructed to avoid exercise
Outcomes	Cardiorespiratory fitness: 12‐minute walk test Strength: 1 repetition maximum Bone mass density: Dual‐energy X‐ray absorptiometry Outcomes measured at baseline and 6 months
Notes	Funding: Not reported Conflict of interest: Not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method of randomisation not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants All outcomes	High risk	Not done
Blinding of personnel/care providers All outcomes	High risk	Not reported Comment: probably not done
Blinding of outcome assessment (detection bias) Fitness outcomes	High risk	Not reported Comment: probably not done
Blinding of outcome assessment (detection bias) All outcomes except fitness outcomes	Unclear risk	No other relevant outcomes
Incomplete outcome data (attrition bias) All outcomes	Low risk	Drop‐out: Intervention group 1 (aerobic): 8.3% (2/24) Intervention group 2 (resistance): 8.7% (2/23) Control group: 8% (2/25) All participants: 8.3% (6/72) No data imputation
Selective reporting (reporting bias)	Unclear risk	No study protocol published
Group similarity at baseline	Low risk	No significant differences
Adherence	Unclear risk	No adherence data available
Contamination	Unclear risk	Not reported. Control group not sedentary before cancer diagnosis