NCT02240836.

Trial name or title	Energy Balance and Breast Cancer Aspects‐II (EBBA‐II)
Methods	RCT, 2 groups
Participants	Newly diagnosed breast cancer patients undergoing adjuvant therapy, DCIS grade 3, stage I + II breast cancer Estimated enrolment: 600 participants
Interventions	12‐month exercise program comprised of strength and endurance training. Exercise groups supervised by experienced physiotherapists, the participants will attend the exercise groups for training 60 min, 2/week. Additionally, home‐based exercise for > = 120 minutes a week, aiming to perform a total of 240 minutes of exercise per week. The control group told to follow standard‐care regimen
Outcomes	Primary: metabolic profile Secondary: Relapse of breast cancer disease, breast cancer‐specific mortality, overall mortality, disease‐free survival, recurrence‐free interval QoL parameters: QoL, fatigue, anxiety, depression Cardiopulmonary function: cardiopulmonary exercise testing (CPET), VO2 max, forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF), diffusing capacity of the lung for carbon monoxide (DLCO)
Starting date	September 2014
Contact information	Inger Thune inger.thune@uit.no
Notes	Estimated primary completion date: May 2016 Planned follow‐up: 10 years