Comparison 1. Y‐set systems versus standard systems.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of patients with peritonitis	7	485	Risk Ratio (M‐H, Random, 95% CI)	0.64 [0.53, 0.77]
2 Peritonitis rate	8	7417	Risk Ratio (M‐H, Random, 95% CI)	0.49 [0.40, 0.61]
3 Number of patients with exit site/tunnel infection	2	184	Risk Ratio (M‐H, Random, 95% CI)	1.02 [0.72, 1.46]
4 Exit‐site/tunnel infection rate	2	2841	Risk Ratio (M‐H, Random, 95% CI)	1.24 [0.91, 1.69]
5 Number of patients switched to HD	2	184	Risk Ratio (M‐H, Random, 95% CI)	0.45 [0.19, 1.05]
6 Number of patients no longer on allocated treatment for whatever reason	2	184	Risk Ratio (M‐H, Random, 95% CI)	1.05 [0.76, 1.46]
7 Number of patients who had CAPD catheter removed	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
8 Number of patients hospitalised (all cause)	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
9 Number of patients hospitalised (peritonitis)	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
10 All‐cause mortality	5	355	Risk Ratio (M‐H, Random, 95% CI)	1.03 [0.48, 2.21]