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. 2014 Aug 13;2014(8):CD003078. doi: 10.1002/14651858.CD003078.pub2

Owen 1992.

Methods RCT
Method of random allocation: not described.
Masking: not mentioned.
Description of withdrawals and dropouts: numbers and reasons clearly stated ‐ treatment group ‐ 20 (died ‐ 3; transplant ‐ 11; haemodialysis ‐ 3; intermittent peritoneal dialysis or other CAPD system ‐ 3); control ‐ 18 (died ‐ 5; transplanted ‐ 3; haemodialysis ‐ 10; transferred to intermittent peritoneal dialysis or CAPD ‐ 0).
Analysis on intention to treat basis: unclear.
Duration of follow‐up (median, range): treatment group ‐ 9 (1‐33) months; control group ‐ 14 (1‐34) months.
 treatment group ‐ 375 patient‐months; control group ‐ 430 patient‐months.
Participants 60 patients commencing CAPD.
30 in treatment group and 30 in control group.
Inclusion criteria: "patients who could tolerate 2L fluid exchanges".
Exclusion criteria: "Significant physical disabilities or severe visual impairment".
Male:female ratio: treatment group ‐ 16:14; control group ‐ 15:15.
Age (median, range): treatment group ‐ 54 (11‐79) years; control group ‐ 56 (16‐75) years.
Interventions Y‐set modification (O‐system "modification of the Y‐system with the ends of the connector joined to each other to form a closed circuit between exchanges"; flush before fill, ends soaked in hypochlorite prior to exchange) vs standard system (luer lock, System II, Baxter)
Outcomes Peritonitis.
 Exit site infection.
 Technique failure
 Training time
Notes Povidone iodine caps used.
Kaplan‐Meir analysis also reported.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear