Skip to main content
. 2013 Jul 9;2013(7):CD006910. doi: 10.1002/14651858.CD006910.pub2

HECTOR.

Trial name or title Topotecan plus carboplatin (TC) versus standard therapy with paclitaxel plus carboplatin (PC) or gemcitabine plus carboplatin (GC) or carboplatin plus pegylated doxorubicin (PLDC): a randomised phase III trial of the NOGGO‐AGO‐Germany‐AGO Austria and GEICO‐GCIG intergroup study (HECTOR)
Methods Phase III multicentre RCT
Participants 550 women with PS ROC.
Interventions Arm 1:TC
Arm 2: GC or PC or PLDC
Outcomes Primary: PFS
Secondary: toxicity
Starting date Accrual from Feb 2007 to Dec 2009
Contact information Sehouli@aol.com
Notes Interim data of the first 200 women were presented at ASCO 2012. However, approx. 78% of control arm received GC and it is not clear how many participants, if any, received the PLDC intervention. We emailed the lead investigator for more information on 13/11/12 and 30/11/12.