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. 2014 May 15;2014(5):CD010681. doi: 10.1002/14651858.CD010681.pub2

GOG 0258.

Study name Carboplatin and paclitaxel with or without cisplatin and radiation therapy in treating patients with endometrial cancer
Methods Phase III multi‐centre open label RCT
Participants Women with high risk endometrial cancer (surgical stage III/IV advanced and stage I/II clear cell or serous papillary)
Interventions Arm 1: cisplatin on days 1 and 29 + EBRT for six weeks. Thereafter, four courses of carbo/paclitaxel. ('sandwich' technique)
Arm 2: carbo/paclitaxel x six courses starting on day 1.
Outcomes RFS, OS, early and late adverse effects, QoL
Starting date June 2009
Contact information Daniela Matei
Notes Adjuvant chemoradiation versus CT.