GOG 0258.
Study name | Carboplatin and paclitaxel with or without cisplatin and radiation therapy in treating patients with endometrial cancer |
Methods | Phase III multi‐centre open label RCT |
Participants | Women with high risk endometrial cancer (surgical stage III/IV advanced and stage I/II clear cell or serous papillary) |
Interventions | Arm 1: cisplatin on days 1 and 29 + EBRT for six weeks. Thereafter, four courses of carbo/paclitaxel. ('sandwich' technique) Arm 2: carbo/paclitaxel x six courses starting on day 1. |
Outcomes | RFS, OS, early and late adverse effects, QoL |
Starting date | June 2009 |
Contact information | Daniela Matei |
Notes | Adjuvant chemoradiation versus CT. |