Comparison 1.

Prevention: Memantine versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Cognitive functioning composite score			Other data	No numeric data
2 Cognitive functioning sub‐tests			Other data	No numeric data
2.1 Short‐term verbal memory			Other data	No numeric data
2.2 Long‐term verbal memory (recall)			Other data	No numeric data
2.3 Long‐term verbal memory (recognition)			Other data	No numeric data
2.4 Trail making test A			Other data	No numeric data
2.5 Trail making test B			Other data	No numeric data
2.6 Verbal fluency			Other data	No numeric data
3 Adverse events	1	509	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.76, 1.32]