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. 2016 Sep 20;2016(9):CD009858. doi: 10.1002/14651858.CD009858.pub2

Summary of findings for the main comparison. Rubber dam versus cotton rolls for restorative treatment in dental patients.

Rubber dam versus cotton rolls for restorative treatment in dental patients
Patient or population: dental patients
 Settings: China and Kenya
 Intervention: rubber dam versus cotton rolls
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) No of participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
Cotton rolls Rubber dam
Survival rate (6 months) 
 assessed clinically and radiographically
 Follow‐up: mean 6 months 765 per 1000 910 per 1000 
 (796 to 1000) RR 1.19 
 (1.04 to 1.37) 162
 (1 study) ⊕⊝⊝⊝
 very low1 There was weak evidence showing that the use of rubber dam might result in higher survival rate of the restorations compared to cotton rolls at 6 months' follow‐up
Weak evidence also indicating the usage of rubber dam might relatively increase the survival rate of restorations after 24 months' follow‐up compared to cotton rolls (HR 0.80, 95% CI 0.66 to 0.97; 559 participants; 1 study; very low‐quality evidence)
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI)
 CI: confidence interval; HR: hazard ratio; RR: risk ratio
GRADE Working Group grades of evidence
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

1 Downgraded 3 times due to being a single study, at high risk of bias and for indirectness: the included study had high risk of bias and was only conducted in China or Kenya population that may not be applicable in other populations.