Methods | Design: Prospective cohort Recruitment: People attending an outpatient clinic Setting: University hospital outpatient clinic, Switzerland Inclusion criteria: Wish to reduce tobacco use or had failed to stop smoking using varenicline, bupropion or NRT in past |
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Participants | TOTAL N: 17 mean 23 cpd, 82% had a psychiatric illness |
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Interventions | Offered an EC with nicotine 59% also reported using NRT or varenicline in addition to EC |
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Outcomes | Smoking cessation and reduction by at least 30% at 12 months (self‐report) Adverse events No significant side effects |
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Notes | Abstract only, hence little detail available Not clear if EC was provided by clinic or if participants had to buy their own |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Prospective cohort |
Allocation concealment (selection bias) | High risk | Not randomized |
Blinding of participants and personnel (performance bias) All outcomes | High risk | No blinding |
Blinding of outcome assessment (detection bias) All outcomes | High risk | No blinding, no biochemical validation used |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Numbers lost to follow‐up not reported |
Selective reporting (reporting bias) | Unclear risk | Unable to determine prespecified outcomes |