Spirito 2004.

Methods	Design: RCT Follow‐up: 3, 6, 12 months Attrition: 10.5%
Participants	Mean age (years): 15.6 Sex: 36% female N participants: 152 Allocation: n = 78 intervention n = 74 control Setting: emergency department of hospital; higher risk patients Country: USA
Interventions	Programme type: motivational interviewing Set‐up: single individual session Key components: exploration of motivation; feedback, establishing goals Duration: 35‐45 min Control: alternative intervention
Outcomes	Outcomes: alcohol‐related injuries; drink‐driving; drinking days per month; drinking quantity; binge drinking frequency; frequency of intoxication past 3 months; alcohol‐related problems Measures: Adolescent Injury Checklist; Young Adult Drinking and Driving Questionnaire; Adolescent Drinking Questionnaire; Adolescent Health Behavior Questionnaire
Funding and Declared Conflicts of Interest	Funded by NIAAA. No information or declarations about potential conflicts of interest
Notes	—
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Patients were randomly assigned to the MI or SC plus assessment condition using a random numbers table
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Incomplete outcome data (attrition bias) All outcomes	Low risk	Low attrition (10.5%)
Selective reporting (reporting bias)	Low risk	All expected outcomes reported
Blinding of participants and personnel (performance bias) All outcomes	High risk	Not possible to blind participants to intervention. Insufficient information to make a judgement about blinding of therapists
Blinding of outcome assessment (detection bias) All outcomes	Low risk	All follow‐up interviews were conducted by research assistants who were blind to treatment group assignment
Unit of Analysis issues	Low risk	Not applicable