Barzoi 2000.

Methods	RCT Setting: Italy Funding: unspecified
Participants	60 ASA 2 or 3 patients scheduled for major surgery with hepato‐biliary neoplastic disease
Interventions	Control group: TEA (T6‐T7; catheter inserted 3 cm passed the needle tip) with bupivacaine 0.125% plus morphine for 36 hours (n = 30) Treatment group: TEA (T6‐T7; catheter inserted 3 cm passed the needle tip) with morphine alone for 36 hours (n = 30) General anaesthesia for all participants
Outcomes	Time to first faeces Vomiting
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"randomised", no details
Allocation concealment (selection bias)	Unclear risk	Not mentioned
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not mentioned
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Treatment was administered by some study authors (GB, SC, BB) and results were analysed by others (GM, SV, GC), who were unaware of the type of analgesic treatment that had been used
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up
Selective reporting (reporting bias)	Low risk	All results provided
Other bias	Low risk	Groups well balanced