Brodner 2001.

Methods	RCT Approved by the ethics committee and informed consent obtained Setting: Denmark Funding: unspecified
Participants	30 patients undergoing radical cystectomy with formation of an ileal neobladder
Interventions	Treatment group: TEA (T9‐T11) with ropivacaine 0.5% during the intraoperative period and 10 mL of ropivacaine 0.2% at the end of surgery. IV piritramide thereafter (n = 15) Control group: IV piritramide (n = 15) All participants received general anaesthesia
Outcomes	VAS on movement at 24, 48 and 72 hours Time to first faeces Anastomotic leak
Notes	Study includes a third group collected after the first 2 groups
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"randomly allocated", no details
Allocation concealment (selection bias)	Unclear risk	Not mentioned
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not mentioned
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not mentioned
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up mentioned
Selective reporting (reporting bias)	Low risk	All results reported
Other bias	Low risk	Groups well balanced except for blood losses