El‐Refai 2003.
Methods | RCT Approved by the ethics committee and informed consent obtained Setting: Egypt Funding: unspecified |
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Participants | 30 ASA 1 or 2 women undergoing total abdominal hysterectomy Exclusion criteria were history of hepatic or renal disease, myocardial infarction within the previous 6 months and general anaesthesia within the previous 3 months |
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Interventions |
Treatment group: lumbar (L3‐L4 or L4‐L5) epidural with 3 mL of 2% lidocaine as a test dose followed by 9 mL of 0.25% bupivacaine for a sensory level at T10, and 5 mL every hour thereafter (n = 15) Control group: IV patient‐controlled analgesia with morphine (n = 15) General anaesthesia for all participants |
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Outcomes | Pain at 30 minutes after surgery: 1.4 ± 1.3 vs 2.4 ± 1.4 | |
Notes | No outcomes of interest measured at our selected time points | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "randomly allocated", no details |
Allocation concealment (selection bias) | Low risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up |
Selective reporting (reporting bias) | Low risk | All results reported |
Other bias | Low risk | Groups well balanced |