Hu 2006.
Methods | RCT Informed consent obtained Setting: China Fundong: departmental resources |
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Participants | 120 patients scheduled for lower abdominal surgery under general anaesthesia Exclusion criteria were reoperation, severe inflammation and immunological disease |
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Interventions |
Treatment group: epidural analgesia (T12‐L1; installed before surgery) with bupivacaine 0.1% and fentanyl 2 mcg/mL through patient‐controlled epidural analgesia: bolus 3 mL, lockout time 10 minutes, basal rate 6 mL/h (n = 40), duration 48 hours Control groups: IM pethidine on request (n = 40) or IV PCA with morphine (n = 40) General anaesthesia for all participants |
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Outcomes | Pain scores at rest and on coughing (taken as on movement) at 24 and 48 hours | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "randomly divided", no details |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up. No failed epidural mentioned |
Selective reporting (reporting bias) | Low risk | All results reported |
Other bias | Low risk | Groups well balanced |