Kentner 1996.
Methods | RCT Approved by the ethics committee Setting: Germany Funding: unspecified |
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Participants | 74 patients undergoing urological surgery through a lower abdominal incision | |
Interventions |
Treatment group: lumbar (L3‐L4; catheter advanced 3 to 4 cm) epidural analgesia with 4 mL of mepivacaine 2% plus epinephrine as a test dose followed by 10 to 16 mL of 0.5% bupivacaine plus 5 to 8 mL every 90 to 120 minutes intraoperatively, and 0.25% bupivacaine for 6 hours after surgery followed by 0.175% bupivacaine at 8 mL/h thereafter for 36 hours plus IV patient‐controlled analgesia with piritramide (n = 37) Control group: IV patient‐controlled analgesia with priritramide (n = 37) |
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Outcomes | Time to first faeces: First bowel movement occurred between postoperative days 3 and 5 with no differences noted between the 2 groups Pain on a 6‐degree scale: Participants in the epidural group had lower pain scores during the first 8 hours |
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Notes | Data not extractable; study authors contacted on 23 June 2015, and informed us that original data were no longer available | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "randomized", no details |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 1 participant given epidural analgesia excluded for catheter dislodgement; 1 participant given opioid analgesia excluded for incomplete data |
Selective reporting (reporting bias) | Low risk | All results reported |
Other bias | Unclear risk | Groups well balanced Not in intention‐to‐treat |