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. 2016 Jul 15;2016(7):CD001893. doi: 10.1002/14651858.CD001893.pub2

Rockemann 1997.

Methods RCT
Approved by the ethics committee
Setting: Germany
Funding: unspecified
Participants 62 patients undergoing abdominal surgery (gastrointestinal mainly)
Exclusion criteria were allergy to 1 of the substances used, age > 65 years, long‐term opioid or corticosteroid use, coagulation disorder and systemic infection
Interventions Treatment group: thoracic epidural analgesia (T7‐T8 to T10‐T11, catheter introduced 5 to 7 cm passed the needle tip, median approach) with bupivacaine 0.25% and sufentanil 2 mcg/mL (0.05 mL/kg; lockout time 10 minutes) (n = 31)
Control group: IV PCA with morphine 2 mg, lockout time 10 minutes (n = 31)
General anaesthesia with propofol, sufentanil, nitrous oxide, enflurane and pancuronium. To increase intestinal motility, participants received metoclopramide 10 mg 3 times daily from postoperative day 1, and prostigmine 1 mg as a short infusion from postoperative day 3. Duration of pain treatment was 101 ± 3 hours
Outcomes Time to first faeces
Pain scores (0 to 10) at rest and on coughing (taken as on movement) at 24, 48 and 72 hours after surgery
Length of hospital stay
Costs
Notes Addiitonal data provided by study authors
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "randomization table"
Allocation concealment (selection bias) Unclear risk Not mentioned
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not mentioned
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not mentioned
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No loss to follow‐up
Selective reporting (reporting bias) Low risk All results provided
Other bias Low risk Groups well balanced