Rutberg 1984.
Methods | RCT Approved by the ethics committee and informed consent obtained Setting: Sweden Funding: governmental (plus a contribution from the industry) |
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Participants | 24 female patients undergoing cholecystectomy | |
Interventions |
Treatment group: TEA (T9‐T10 or T10‐T11) with bupivacaine 0.5% before surgery and 0.25% to 0.375%, 5 to 8 mL to maintain segmental blockade from T4 to L3 (n = 8) for 24 hours
Control group: epidural morphine 4 mg in 7 mL of saline, repeated every 10 hours (n = 8), and postoperative IV morphine 2.5 mg as required (n = 8) General anaesthesia for all participants |
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Outcomes | VAS scores at 6 and 24 hours (not clearly mentioned, taken as at rest) | |
Notes | Study includes a third group referred to as "control" group and not retained for the purpose of this meta‐analysis | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "randomly allocated", no details |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up and no epidural failure mentioned |
Selective reporting (reporting bias) | Low risk | All results provided |
Other bias | Low risk | Groups well balanced |