Taqi 2007.
Methods | RCT Approved by the ethics board and written consent obtained from all patients Setting: Canada Funding: charity |
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Participants | 50 patients scheduled for elective laparoscopic colorectal surgery for benign and malignant colorectal lesions | |
Interventions |
Treatment group: TEA (T8‐T9) with bupivacaine 0.5% and 0.25% during surgery and bupivacaine 0.1% plus fentanyl 3 mcg/mL for 72 hours after surgery (n = 25) Control group: IV PCA with morphine (n = 25) General anaesthesia for all participants. Both groups also received 500 mg naproxen twice a day orally or rectally for 4 days, and acetaminophen 1 gram 4 times a day for 4 days |
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Outcomes | Time to first flatus Time to first faeces Vomiting VAS at rest and on movement (walking) at 24 and 48 hours |
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Notes | Study authors contacted for additional information on 12 July 2014, but did not reply | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "randomized", no details |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | High risk | "patients were not blinded" |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Not blinded |
Incomplete outcome data (attrition bias) All outcomes | Low risk | "All the patients enrolled in the research project completed the study" "There were no epidural failures (dislodgement, leak, disconnection) during the postoperative period" |
Selective reporting (reporting bias) | Low risk | All results reported |
Other bias | Low risk | Demographic characteristics and clinical data related to preoperative health status, diagnosis and type of surgery, and preoperative nutritional status, were similar in the 2 groups |