Thorén 1989.
Methods | RCT Approved by the ethics committee and written informed consent obtained Setting: Sweden Funding: governmental |
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Participants | 22 ASA 1 or 2 female patients undergoing hysterectomy | |
Interventions |
Treatment group: TEA (T12‐L1 with the catheter inserted 2 to 3 cm into the epidural space) with bupivacaine 0.5% during surgery, and 0.25% 8 mL/h for 42 hours (n = 11)
Control group: TEA (T12‐L1 with the catheter inserted 2 to 3 cm into the epidural space) with morphine 4 mg bolus, 2 mg on request for 42 hours (n = 11) All participants operated under general anaesthesia |
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Outcomes | Time to first flatus (hours) Time to first faeces (hours) VAS scores at day 1 (taken as at rest) Length of hospital stay (days) |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Before operation, participants were randomly allocated to 2 groups |
Allocation concealment (selection bias) | Unclear risk | Before operation, participants were randomly allocated to 2 groups |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No loss to follow‐up |
Selective reporting (reporting bias) | Low risk | All results reported |
Other bias | Low risk | Groups well balanced |