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. 2016 Jul 15;2016(7):CD001893. doi: 10.1002/14651858.CD001893.pub2

Tsui 1997.

Methods RCT
Approved by the ethics committee and written informed consent obtained from all patients
Setting: China
Funding: unspecified
Participants 120 ASA class 1 or 2 female patients scheduled for gynaecological lower abdominal operations
 through a vertical midline incision
Interventions Treatment group: LEA (L2‐L3 or L3‐L4) with bupivacaine 0.0625% and fentanyl 3.3 mcg/mL adjusted for VAS scores < 3/10 at rest for 48 hours (n = 57)
Control group: IV PCA with morphine adjusted for VAS scores < 3/10 at rest (n = 54)
General anaesthesia for all participants
Outcomes Vomiting
Notes 32% of participants in the epidural group had limb weakness
Study authors contacted for additional information. Replied that original data are no longer available
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "randomly allocated", no details
Allocation concealment (selection bias) Unclear risk "Before the preoperative visit, patients were randomly allocated"
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not mentioned
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not mentioned
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 9 dropped out owing to blockage of the IV cannula for PCA administration (n = 5), extrusion of the epidural catheter during the study period (n = 2) or failure to receive a vertical midline incision (n = 2)
Selective reporting (reporting bias) Low risk All results reported
Other bias Unclear risk Groups well balanced
Not in intention‐to‐treat