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. 2016 Jul 15;2016(7):CD001893. doi: 10.1002/14651858.CD001893.pub2

Wallin 1986.

Methods RCT
Approved by the ethics committee and informed consent obtained
Setting: Sweden
Funding: governmental (plus a contribution from industry)
Participants 30 patients scheduled for elective cholecystectomy; 3 loss to follow‐up (27 analysed: 17 female and 10 male)
Interventions Treatment group: TEA (T12‐L1; catheter inserted 3 to 4 cm passed the needle tip) with bupivacaine 0.5% started before the incision, and 0.25% intermittent injection of 10 to 14 mL every 3 hours for 24 hours after surgery (n = 12)
 Control group: postoperative IM pentazocine 30 to 60 mg on request (n = 15)
General anaesthesia for all participants
Outcomes Time of first flatus (hours)
Time of first stool (hours)
Notes Study authors contacted for additional information on 23 July 2014, but did not reply
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "the Mudy was randomized", no details
Allocation concealment (selection bias) Unclear risk Not mentioned
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not mentioned
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not mentioned
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk 3 in the epidural group lost to follow‐up (failed epidural)
Selective reporting (reporting bias) Low risk All results provided
Other bias Unclear risk Groups well balanced
Not in intention‐to‐treat (n = 12 for epidural in the results)