Wallin 1986.
Methods | RCT Approved by the ethics committee and informed consent obtained Setting: Sweden Funding: governmental (plus a contribution from industry) |
|
Participants | 30 patients scheduled for elective cholecystectomy; 3 loss to follow‐up (27 analysed: 17 female and 10 male) | |
Interventions |
Treatment group: TEA (T12‐L1; catheter inserted 3 to 4 cm passed the needle tip) with bupivacaine 0.5% started before the incision, and 0.25% intermittent injection of 10 to 14 mL every 3 hours for 24 hours after surgery (n = 12)
Control group: postoperative IM pentazocine 30 to 60 mg on request (n = 15) General anaesthesia for all participants |
|
Outcomes | Time of first flatus (hours) Time of first stool (hours) |
|
Notes | Study authors contacted for additional information on 23 July 2014, but did not reply | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "the Mudy was randomized", no details |
Allocation concealment (selection bias) | Unclear risk | Not mentioned |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | 3 in the epidural group lost to follow‐up (failed epidural) |
Selective reporting (reporting bias) | Low risk | All results provided |
Other bias | Unclear risk | Groups well balanced Not in intention‐to‐treat (n = 12 for epidural in the results) |