Basnet 2010.

Methods	RCT Painful intervention: venipuncture Study location: Neonatal ward of Tribhuvan University Teaching Hospital, Kathmandu, Nepal Study period: February to August 2006
Participants	50 term infants aged between 12 h to 8 days Mean post‐natal age: 59.92 h no treatment group; 68.76 h sucrose group
Interventions	No treatment group (n = 25) Sucrose group (n = 25): received 2 ml of 30% sucrose orally 2 minutes before venipuncture
Outcomes	DAN score, duration of cry, number of infants crying
Notes	Data for DAN scores were reported as median and IQRs. Duration of cry was reported as mean and SD and was included in meta‐analyses
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Used random numbers from 1 to 50 developed from a random number table
Allocation concealment (selection bias)	High risk	Authors did not report whether the opaque, sealed envelopes used to allocate participants were sequentially numbered
Blinding (performance bias and detection bias) All outcomes	Low risk	Personnel blinded
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Outcome assessors blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	Outcome reported for all randomized infants
Selective reporting (reporting bias)	Unclear risk	One rating scale (DAN) listed in methods section and is reported in results table. The study protocol was not available to us so we could not judge whether there were any deviations from it
Other bias	Low risk	Appears free of other bias