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. 2016 Jul 15;2016(7):CD001069. doi: 10.1002/14651858.CD001069.pub5

Yilmaz 2010.

Methods RCT
Painful intervention: heel lance
Study location: Trabzon Delivery and Children's Diseases Hospital, Erzurum, Turkey
Study period: February 2007 to January 2008
Participants 120 infants GA 37 to 42 weeks
Sucrose group (n = 30): mean PMA (SD) 39.10 weeks (0.71)
Mother's milk group (n = 30): mean PMA (SD) 39.10 weeks (1.03)
Pacifier group (n = 30): mean PMA (SD) 39.20 weeks (0.93)
Control group (n = 30): mean PMA (SD) 39.67 weeks(0.80)
Interventions Sucrose group: 2 mL 20% sucrose via syringe 2 min before the procedure (using a syringe with the needle removed and avoiding contact of the syringe with the mouth and lips)
Mother's milk group: 2 mL mother's milk via syringe 2 min before the procedure (using a syringe with the needle removed and avoiding contact of the syringe with the mouth and lips)
Pacifier group: given a pacifier
Control group: newborns were in their mothers' lap; no interventions were made before the painful procedure
Outcomes NIPS score, HR, respiratory rate, crying time. Data were presented according to different procedure times and could not be used in meta‐analyses
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Did not specify method of randomization
Allocation concealment (selection bias) Unclear risk Did not specify method of allocation concealment
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Did not report on blinding of personnel
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Did not report on blinding of outcome assessors
Incomplete outcome data (attrition bias) 
 All outcomes Low risk There were no withdrawals
Selective reporting (reporting bias) Unclear risk The study protocol was not available to us so we could not judge whether there were any deviations from it
Other bias Low risk Appears free of other bias