Study	Reason for exclusion
Applegate 2003	Irrelevant outcome ‐ participation at appointment.
Barakat 2007	Not a RCT.
Boroffice 1991	Irrelevant outcomes; attitudes not listed in outcomes assessed.
Carpenter 2007	Unsuccessful in contacting authors for necessary information.
Chernoff 2002	Irrelevant intervention; buddy system not considered an educational program.
Daly 2012	Irrelevant intervention ‐ pharmacological.
Ireys 2001	Irrelevant intervention; buddy system not considered an educational program.
Jenerette 2014	Irrelevant outcome ‐ stigma.
Kaslow 1997	Not a RCT.
King 2006	Irrelevant intervention; memory strategy not considered an educational program.
King 2007	Irrelevant intervention, memory strategy not considered an educational program.
Lemanek 2009	Irrelevant intervention; massage therapy not considered an educational program.
Mendolia 1993	Not a RCT.
Oyeku 2005	Irrelevant participant ‐ clinician.
Oyeku 2005 b	Irrelevant participant ‐ clinician.
Oyeku 2010	Irrelevant participant ‐ clinician.
Radcliffe 2007	Irrelevant study type, outcome.
Robinson 1990	Unsuccessful in contacting authors for necessary information.
Schatz 2004	Unsuccessful in contacting authors for necessary information.
Thomas 2013	Irrelevant intervention.
Wilkie 2013	Irrelevant participants; SS and AS analysed together.
Yang 2000	Irrelevant participants ‐ SCT.
Yerys 2003	Irrelevant intervention; memory strategy not considered an educational program.

RCT: randomized controlled trial
 SCT: sickle cell trait