| Trial name or title |
Comparison of four skin preparation strategies to prevent catheter‐related infection in intensive care unit (CLEAN trial): a study protocol for a randomized controlled trial |
| Methods |
"A prospective multicenter, 2 × 2 factorial, randomized‐controlled, assessor‐blind trial" |
| Participants |
Setting: 11 intensive care units in 6 French hospitals. Participants: All adult patients aged over 18 years requiring the insertion of 1 or more of the following: peripheral arterial catheter, non‐tunnelled central venous catheter, haemodialysis catheter and arterial pulmonary catheter |
| Interventions |
Patients are allocated to 1 of the 4 skin preparation strategies: 2% chlorhexidine/70% isopropyl alcohol or 5% povidone iodine/69% ethanol, with and without prior skin scrubbing |
| Outcomes |
Catheter‐related BSI, catheter colonisation, cutaneous tolerance, length of hospitalisation, mortality and cost. |
| Starting date |
October 2012, lasting approximately 14 months |
| Contact information |
Corresponding author: Olivier Mimoz o.mimoz@chu‐poitiers.fr |
| Notes |
Clinicaltrials.gov number NCT01629550. Protocol published in Trials, 2013:14: 114 |
