Analysis 1.1.

Comparison 1 Hydromorphone versus oxycodone, Outcome 1 Participant‐reported pain intensity (skewed data).

Participant‐reported pain intensity (skewed data)

Study	Interventions	Least square mean	Standard deviation	n
Visual analogue scale (VAS) endpoint pain intensity score (high score = poor outcome)
Hagen 1997	Hydromorphone	28.86	17.08	19
Hagen 1997	Oxycodone	30.30	25.33	12
Brief Pain Inventory worst pain in past 24 hours (change score)
Yu 2014	Hydromorphone	‐1.8	3.29	40
Yu 2014	Oxycodone	‐1.7	3.91	41