| Methods |
Double‐blind, randomised, placebo‐controlled trial |
| Participants |
95 participants who presented to general practice complaining of sore throat |
| Interventions |
Oral sulphonamide or similar looking and tasting oral placebo, for the control condition |
| Outcomes |
Incidence of sinusitis or quinsy or symptoms of sore throat or fever |
| Notes |
Antipyretic use was not documented |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Randomised by random numbering of bottles |
| Allocation concealment (selection bias) |
Low risk |
|
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
Double‐blind study design |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
|
| Selective reporting (reporting bias) |
Unclear risk |
Antipyretic use was not documented |
