Methods |
Double‐blind, randomised, placebo‐controlled trial |
Participants |
561 participants aged 15 to 60 years presenting with sore throat of less than 7 days duration |
Interventions |
Penicillin V for 7 days, penicillin V for 3 days followed by 4 days of placebo or placebo or 7 days |
Outcomes |
Resolution of symptoms and recurrence of sore throat |
Notes |
Author was contacted for data that could be used in the meta‐analysis |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Low risk |
Computer‐generated random sequence |
Allocation concealment (selection bias) |
Low risk |
|
Blinding (performance bias and detection bias)
All outcomes |
Low risk |
Double‐blind study design |
Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
|
Selective reporting (reporting bias) |
Low risk |
All relevant outcomes reported |