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. 2016 Oct 12;2016(10):CD002042. doi: 10.1002/14651858.CD002042.pub4

Fan 2014.

Methods Randomised clinical trial
Participants 186 participants 65 years of age or older undergoing elective unilateral total hip replacement
  • Liberal group: n = 92; mean (SD) age = 75 (6) years

  • Restrictive group: n = 94; mean (SD) age = 73 (7) years

Interventions
  • The liberal group received transfusion to maintain Hg greater than 10 g/dL.

  • The restrictive group received transfusion for Hg less than 8 g/dL or when symptoms of anaemia developed.

Outcomes Delirium, cerebrovascular accident, cardiac failure, myocardial infarction, pulmonary embolism, pneumonia, superficial wound infection, urinary tract infection, acute renal failure
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk The trial used a random number table.
Allocation concealment (selection bias) Low risk The trial used a sealed envelope technique.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk The blinding of participants and personnel was not described.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk The blinding of outcome assessment was not described.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk There was a low rate of missing data.
Selective reporting (reporting bias) Low risk No reporting bias was apparent.
Other bias Low risk No other bias was apparent.