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. 2016 Oct 12;2016(10):CD002042. doi: 10.1002/14651858.CD002042.pub4

Gregersen 2015.

Methods Randomised clinical trial
Participants Participants aged 65 years or older undergoing hip fracture surgery and who had postoperative Hb levels between 9.7 g/dL and 11.3 g/dL during the first 6 postoperative days
  • Liberal: n = 140; mean age (SD) = 88 (6.9) years

  • Restrictive: n = 144; mean age (SD) = 86 (6.8) years

Interventions The liberal transfusion group received transfusion when Hb was less than 11.3 g/dL, and the restrictive transfusion group received transfusion when Hg was less than 9.7 g/dL.
Outcomes The primary outcome was recovery from physical disabilities, with 3 tools being used to measure physical performance: Modified Barthel index, New Mobility score and cumulated ambulation score, total number of infections (pneumonia, urinary tract infection, other), cognition, depression, quality of life, modified Barthels index, and comprehensive frailty index.
Notes 3 publications reported results.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random sequence generation was not specifically stated, but it was likely since a clinical trial support system was used.
Allocation concealment (selection bias) Low risk A web‐based randomisation system was used.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk The participants were blinded but not the clinicians.
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk The assessor was blinded.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk The outcome data appeared to be complete.
Selective reporting (reporting bias) Low risk No reporting bias was apparent.
Other bias Low risk No other biases were apparent.