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. 2016 Oct 12;2016(10):CD002042. doi: 10.1002/14651858.CD002042.pub4

Prick 2014.

Methods Randomised controlled trial, not blinded
Participants Postpartum haemorrhage (blood loss of ≥1000 ml or a decrease in Hb concentration of ≥1.9 g/dL, or both) and had an Hb between 4.8 g/dL and 7.9 g/dL 12 to 24 hours after delivery
  • Liberal: n = 258; mean age (SD) = 30.7 (5.0) years

  • Non‐intervention: n = 261; mean age (SD) = 30.9 (5.3) years

Interventions In the liberal group, participants received at least 1 unit of red blood cells; the trialists aimed to reach an Hb concentration of at least 8.9 g/dL. In the restrictive group, participants received no transfusion.
Outcomes Primary outcome was physical fatigue 3 days postpartum using the Multidimensional Fatigue Inventory scale
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk The use of random sequence generation was not stated.
Allocation concealment (selection bias) Low risk The trial used a web‐based application with block randomisation of variable block size.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Participants were not blinded.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk The primary outcome was based on a questionnaire.
Incomplete outcome data (attrition bias) 
 All outcomes High risk 20% of data for the primary outcome was missing.
Selective reporting (reporting bias) Low risk No reporting bias was apparent.
Other bias Low risk No other biases were apparent.