Tay 2011.
Trial name or title | Transfusion of red cells in hematopoietic stem cell transplantation: the TRIST study |
Methods | Randomised clinical trial stratified by centre and type of transplant |
Participants | Participants undergoing hematopoietic stem cell transplantation |
Interventions | Restrictive (target haemoglobin of 7 g/dL to 9 g/dL) or liberal (target haemoglobin of 9 g/dL to 11 g/dL) RBC transfusion strategy, based on daily haemoglobin values up to 100 days post‐transplant |
Outcomes | Feasibility and clinical outcomes including transfusion requirements, transplant‐related mortality, maximum grade of acute graft versus host disease, veno‐occlusive disease, serious infections, Bearman Toxicity Score, bleeding, quality of life, number of hospitalisations, and number of intensive care unit admissions. |
Starting date | March 2011 |
Contact information | Jason Tay, MD Department of Medicine University of Calgary |
Notes | ‐ |
Abbreviations
Hb = haemoglobin ICU = intensive care unit MDS = myelodysplastic syndromes QOL = quality of life RBC = red blood cells TBSA = total body surface area